Scientific and Clinical Studies
Theralac® Probiotic Strains
Scientific and Clinical Studies
Theralac® Probiotic Strains
Lactobacillus acidophilus strain LA-1 (10 Billion CFU per Capsule)
References:
Human strain on deposit at the American Type Culture
Collection (ATCC) as SD5221.
Wagner R., Warner, T.,Robert, L., Farmer, J. and Balish, E.
(1997). Colonization of congenitally immunodeficient mice with probiotic
bacteria. Infect. Immun. 65:3345-3351.
Sui, J., Leighton, S., Busta, F. and Brady L. (2002). 16s
ribosomal DNA analysis of the fecal lactobacilli composition on human subjects
consuming a probiotic strain Lactobacillus
acidophilus NCFM®. J. Appl. Microbiol. 93:907-912.
Varcoe, J., Zook, C., Sui, J., Leighton, S., Busta, F. and
Brady L. (2002) Variable response to exogenous Lactobacillus acidophilus NCFM® consumed in different vehicles. J.
Appl. Microbiol. 93:900-906.
Greene, J.D. and Klaenhammer, T.R. (1994). Factors involved
in adherence of lactobacilli to human Caco-2 cells. Appl. Environ. Microbiol.
60:4487-4494.
Kleeman, E.G. and Klaenhammer, T.R. (1982). Adherence of Lactobacillus species to human fetal
intestinal cells. J. Dairy Sci. 65:2063-2069.
Gilliland, S.E., and Speck, M.L. (1977). Deconjugation of
Bile Acids by Intestional Lactobacilli. Appl. Environ. Microbiol., 33(1):15-18.
Goldin, B.R., Swenson, L., Dwyer, J., Sexton, M. and
Gorbach, S.L. (1980). Effect of diet and Lactobacillus
acidophilus supplements on human fecal bacterial enzymes. J. Natl. Cancer
Inst. 64(2):255-261.
Varcoe, J.J., Krejcarek, G., Busta, F. and Brady, L. (2003).
Prophylactic feeding of Lactobacillus
acidophilus NCFM® to mice attenuates overt colonic hyperplasia. J. Food
Prot. 66(3):457-465.
Kim, H.S. and Gilliland, S.E. (1983). Lactobacillus acidophilus as a dietary adjunct for milk to aid
lactose digestion in humans. J. Dairy Science. 66(5):959-966.
Dunn, S.R., Simenhoff, M.L., Ahmed, K.E., Gaughan, W.J.,
Eltayeb, B.O., Fitzpatrick, M.-E.D., Emery, S.M., Ayres, J.W. and Holt, K.E.
(1998). Effect of oral administration of freeze-dried Lactobacillus acidophilus on small bowel bacterial overgrowth in
patients with end stage kidney disease: reducing uremic toxins and improving
nutrition. Int. Dairy J. 8:545-553.
Wagner, R.D., Pierson, C., Warner, T., Dohnalek, M., Farmer,
J., Roberts, L., Hilty, M. and Balish, E. (1997). Biotherapeutic effects of
probiotic bacteria on candidasis in immunodeficient mice. Infect. Immun.
65(10):4165-4172.
Tejada-Simon, M.V., Lee, J.H., Ustunol, Z. and Pestka, J.J.
(1999). Injestion of yogurt containing Lactobacillus
acidophilus and Bifidobacterium
to potentiate immunoglobulin. A response to cholera in mice. J. Dairy Sci.
82:649-660.
Wagner, R.D., Pierson, C., Warner, T., Dohnalek, M., Hilty,
M. and Balish, E. (2000). Probiotic effects of feeding heat-killed Lactobacillus acidophilus and Lactobacillus casei to Candida albicans-colonized
immunodeficient mice. J. Food Prot. 63(5):638-644.
Engelbrektson, A., Korzenik, J.R., Pittler, A., Sanders,
M.E., Klaenhammer, T.R., Leyer, G. and Kitts, C.L. (2009). Probiotics to
minimize the disruption of faecal microbiotia in healthy subjects undergoing
antibiotic therapy. J. Medical Microbiology 58:663-670.
Sanders, M.E., Walker,
D.C., Walker, K.M., Aoyama, K.
and Klaenhammer, T.R. (1996). Performance of commercial cultures in fluid milk
applications. J. Dairy Sci. 79:943-955. (Strain LH1=NCFM®).
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